Compound class:
Synthetic organic
Comment: IT-62-B is an anthracycline antibacterial that is produced by Streptomyces sp. IT-62 [1-2]. It has moderate activity against Gram-positive bacteria and has antitumour activity in vitro.
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References |
1. Kawauchi T, Sasaki T, Yoshida K, Matsumoto H, Chen RX, Huang MY, Tsuchiya KS, Otani T. (1997)
A new anthracycline antibiotic, IT-62-B, converts the morphology of ras-transformed cells back to normal: taxonomy, fermentation, isolation, structure elucidation and biological characterization. J Antibiot, 50 (4): 297-303. [PMID:9186553] |
2. Tsuchiya KS, Ishii T, Ikeno S, Kunimoto S, Kawauchi T, Otani T, Hori M. (1997)
Inhibition of anchorage-independent growth of tumor cells by IT-62-B, a new anthracycline. J Antibiot, 50 (10): 853-9. [PMID:9402991] |