PF-07062119   Click here for help

GtoPdb Ligand ID: 11125

Compound class: Antibody
Comment: PF-07062119 is a bispecific T cell-engaging (BiTE) monoclonal antibody that is being developed by Pfizer [1]. It simultaneously binds to CD3ε on T cells and GUCY2C-positive cancer cells.
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1. Mathur D, Root AR, Bugaj-Gaweda B, Bisulco S, Tan X, Fang W, Kearney JC, Lucas J, Guffroy M, Golas J et al.. (2020)
A Novel GUCY2C-CD3 T-Cell Engaging Bispecific Construct (PF-07062119) for the Treatment of Gastrointestinal Cancers.
Clin Cancer Res, 26 (9): 2188-2202. [PMID:31996389]