Synonyms: ANB-011 | dostarlimab-gxly | Jemperli® | TSR-042 | WBP-285
dostarlimab is an approved drug (EMA & FDA (2021))
Compound class:
Antibody
Comment: Dostarlimab is a humanized, IgG4κ programmed cell death 1 (PD-1) blocking monoclonal antibody from GlaxoSmithKline.
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References |
1. Oaknin A, Tinker AV, Gilbert L, Samouëlian V, Mathews C, Brown J, Barretina-Ginesta MP, Moreno V, Gravina A, Abdeddaim C et al.. (2020)
Clinical Activity and Safety of the Anti-Programmed Death 1 Monoclonal Antibody Dostarlimab for Patients With Recurrent or Advanced Mismatch Repair-Deficient Endometrial Cancer: A Nonrandomized Phase 1 Clinical Trial. JAMA Oncol, 6 (11): 1766-1772. [PMID:33001143] |