dostarlimab   Click here for help

GtoPdb Ligand ID: 11518

Synonyms: ANB-011 | dostarlimab-gxly | Jemperli® | TSR-042 | WBP-285
Approved drug Immunopharmacology Ligand
dostarlimab is an approved drug (EMA & FDA (2021))
Compound class: Antibody
Comment: Dostarlimab is a humanized, IgG4κ programmed cell death 1 (PD-1) blocking monoclonal antibody from GlaxoSmithKline.
References
1. Oaknin A, Tinker AV, Gilbert L, Samouëlian V, Mathews C, Brown J, Barretina-Ginesta MP, Moreno V, Gravina A, Abdeddaim C et al.. (2020)
Clinical Activity and Safety of the Anti-Programmed Death 1 Monoclonal Antibody Dostarlimab for Patients With Recurrent or Advanced Mismatch Repair-Deficient Endometrial Cancer: A Nonrandomized Phase 1 Clinical Trial.
JAMA Oncol, 6 (11): 1766-1772. [PMID:33001143]