Synonyms: SCO267
Compound class:
Synthetic organic
Comment: SCO-267 is a GPR40 full agonist [1]. Agonist activation of GPR40 (which stimulates secretion of insulin and incretin) is considered to be an attractive mechanism for promoting glycemic control in the treatment of type 2 diabetes mellitus.
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References |
1. Furukawa H, Miyamoto Y, Hirata Y, Watanabe K, Hitomi Y, Yoshitomi Y, Aida J, Noguchi N, Takakura N, Takami K et al.. (2020)
Design and Identification of a GPR40 Full Agonist (SCO-267) Possessing a 2-Carbamoylphenyl Piperidine Moiety. J Med Chem, 63 (18): 10352-10379. [PMID:32900194] |