INSL5 analogue 13   Click here for help

GtoPdb Ligand ID: 11915

Compound class: Peptide
Comment: This is an INSL5 analogue that has a simplified A-chain connected to the B-chain by two disulfide bonds [1]. Its A-chain peptide sequence is hINSL5: A8-21 (T15K).
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References
1. Patil NA, Hughes RA, Rosengren KJ, Kocan M, Ang SY, Tailhades J, Separovic F, Summers RJ, Grosse J, Wade JD et al.. (2016)
Engineering of a Novel Simplified Human Insulin-Like Peptide 5 Agonist.
J Med Chem, 59 (5): 2118-25. [PMID:26824523]
2. Praveen P, Bathgate RAD, Hossain MA. (2019)
Engineering of chimeric peptides as antagonists for the G protein-coupled receptor, RXFP4.
Sci Rep, 9 (1): 17828. [PMID:31780677]