Synonyms: BMS820132 | compound 31 [PMID: 35179904]
Compound class:
Synthetic organic
Comment: BMS-820132 is an investigational oral glucokinase (hexokinase 4) partial activator that was designed for potential to treat type 2 diabetes mellitus (T2DM) [1].
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References |
1. Shi Y, Wang Y, Meng W, Brigance RP, Ryono DE, Bolton S, Zhang H, Chen S, Smirk R, Tao S et al.. (2022)
Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)-1H-pyrazol-1-yl)methyl)phosphonate (BMS-820132). J Med Chem, 65 (5): 4291-4317. [PMID:35179904] |