Compound class:
Synthetic organic
Comment: This is the fluorescent metabolite of CYP3A4 fluorogenic substrate F8 [1]. It fluoresces at a wavelength of 555 nm. F8 can be used to monitor CYP3A4 activity in living cells and tissue preparations.
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References |
1. He RJ, Tian ZH, Huang J, Sun MR, Wei F, Li CY, Zeng HR, Zhang F, Guan XQ, Feng Y et al.. (2023)
Rationally Engineered CYP3A4 Fluorogenic Substrates for Functional Imaging Analysis and Drug-Drug Interaction Studies. J Med Chem, 66 (10): 6743-6755. [PMID:37145039] |