Synonyms: JL-02-0111
Compound class:
Synthetic organic
Comment: JL-2-39 is a high affinity, low potency μ opioid receptor (MOR) agonist [1-2].
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References |
1. Lutz JA, Sulima A, Gutman ES, Bow EW, Luo D, Kaska S, Prisinzano TE, Paronis CA, Bergman J, Imler GH et al.. (2023)
Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans. Molecules, 28 (12): 4795. [PMID:37375350] |
2. Santos EJ, Nassehi N, Bow EW, Chambers DR, Gutman ES, Jacobson AE, Lutz JA, Marsh SA, Rice KC, Sulima A et al.. (2023)
Role of efficacy as a determinant of locomotor activation by mu-opioid receptor (MOR) ligands in female and male mice. II. Effects of novel MOR-selective phenylmorphans with high-to-low MOR efficacy. Pharmacol Res Perspect, 11 (4): e01111. [PMID:37381112] |