Compound class:
Synthetic organic
Comment: The structure for tacaciclib was obtained from proposed INN list 129 (August 2023), where it is described as cyclin-dependent kinase inhibitor and antineoplastic agent. The structure is calimed in patent WO2022130304A1, for potential to treat cancer or other proliferative diseases that are mediated by CDK7 [1]. Interogation of online information suggests that this compound may be XL102 (formerly AUR102), an orally bioavailable covalent CDK7 inhibitor that was acquired by Exelixis, from Aurigene, in late 2020.
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References |
1. Bhat U, Bokalial R, badiger SE, Devanathan K. (2022)
Cocrystal of a cdk inhibitor. Patent number: WO2022130304A1. Assignee: Aurigene Discovery Technologies Ltd.. Priority date: 17/12/2021. Publication date: 23/06/2022. |