Compound class:
Synthetic organic
Comment: Makomakinol is a novel alkaloid discovered as a minor constituent in the traditional herbal remedy made from Aristotelia chilensis (maqui) leaves [1]. The absolute configuration was determined to be (12S,14R,16S).
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References |
1. Pérez R, Figueredo C, Burgos V, Cabrera-Pardo JR, Schmidt B, Heydenreich M, Koch A, Deuis JR, Vetter I, Paz C. (2023)
Natural Compounds Purified from the Leaves of Aristotelia chilensis: Makomakinol, a New Alkaloid and the Effect of Aristoteline and Hobartine on NaV Channels. Int J Mol Sci, 24 (21). [PMID:37958488] |