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Synonyms: HS 014
Compound class: Peptide or derivative
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Schiöth HB, Muceniece R, Mutulis F, Bouifrouri AA, Mutule I, Wikberg JE. (1999)
Further pharmacological characterization of the selective melanocortin 4 receptor antagonist HS014: comparison with SHU9119.
Neuropeptides, 33 (3): 191-6. [PMID:10657491]
2. Schiöth HB, Mutulis F, Muceniece R, Prusis P, Wikberg JE. (1998)
Discovery of novel melanocortin4 receptor selective MSH analogues.
Br. J. Pharmacol., 124 (1): 75-82. [PMID:9630346]
3. Skuladottir GV, Jonsson L, Skarphedinsson JO, Mutulis F, Muceniece R, Raine A, Mutule I, Helgason J, Prusis P, Wikberg JE et al.. (1999)
Long term orexigenic effect of a novel melanocortin 4 receptor selective antagonist.
Br. J. Pharmacol., 126 (1): 27-34. [PMID:10051117]