Ro01-6128

Ligand id: 1386

Name: Ro01-6128

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 55.4
Molecular weight 283.12
XLogP 3.95
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Knoflach F, Mutel V, Jolidon S, Kew JN, Malherbe P, Vieira E, Wichmann J, Kemp JA. (2001)
Positive allosteric modulators of metabotropic glutamate 1 receptor: characterization, mechanism of action, and binding site.
Proc Natl Acad Sci U S A., 98: 13402-13407. [PMID:11606768]