pancreatic polypeptide   Click here for help

GtoPdb Ligand ID: 1512

Abbreviated name: PP
Species: Human
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: pancreatic polypeptide

1. Bard JA, Walker MW, Branchek TA, Weinshank RL. (1995)
Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY.
J Biol Chem, 270 (45): 26762-5. [PMID:7592911]
2. Dumont Y, Thakur M, Beck-Sickinger A, Fournier A, Quirion R. (2003)
Development and characterization of a highly selective neuropeptide Y Y5 receptor agonist radioligand: [125I][hPP1-17, Ala31, Aib32]NPY.
Br J Pharmacol, 139 (7): 1360-8. [PMID:12890716]
3. Gehlert DR, Schober DA, Gackenheimer SL, Beavers L, Gadski R, Lundell I, Larhammar D. (1997)
[125I]Leu31, Pro34-PYY is a high affinity radioligand for rat PP1/Y4 and Y1 receptors: evidence for heterogeneity in pancreatic polypeptide receptors.
Peptides, 18 (3): 397-401. [PMID:9145427]
4. Hu Y, Bloomquist BT, Cornfield LJ, DeCarr LB, Flores-Riveros JR, Friedman L, Jiang P, Lewis-Higgins L, Sadlowski Y, Schaefer J et al.. (1996)
Identification of a novel hypothalamic neuropeptide Y receptor associated with feeding behavior.
J Biol Chem, 271 (42): 26315-9. [PMID:8824284]
5. Lundell I, Blomqvist AG, Berglund MM, Schober DA, Johnson D, Statnick MA, Gadski RA, Gehlert DR, Larhammar D. (1995)
Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY.
J Biol Chem, 270 (49): 29123-8. [PMID:7493937]
6. Tough IR, Holliday ND, Cox HM. (2006)
Y(4) receptors mediate the inhibitory responses of pancreatic polypeptide in human and mouse colon mucosa.
J Pharmacol Exp Ther, 319 (1): 20-30. [PMID:16807358]
7. Walker MW, Smith KE, Bard J, Vaysse PJ, Gerald C, Daouti S, Weinshank RL, Branchek TA. (1997)
A structure-activity analysis of the cloned rat and human Y4 receptors for pancreatic polypeptide.
Peptides, 18 (4): 609-12. [PMID:9210181]
8. Yan H, Yang J, Marasco J, Yamaguchi K, Brenner S, Collins F, Karbon W. (1996)
Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.
Proc Natl Acad Sci USA, 93 (10): 4661-5. [PMID:8643460]