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Compound class: Peptide or derivative
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Larhammar D, Blomqvist AG, Yee F, Jazin E, Yoo H, Wahlested C. (1992)
Cloning and functional expression of a human neuropeptide Y/peptide YY receptor of the Y1 type.
J. Biol. Chem., 267 (16): 10935-8. [PMID:1317848]
2. Lundell I, Blomqvist AG, Berglund MM, Schober DA, Johnson D, Statnick MA, Gadski RA, Gehlert DR, Larhammar D. (1995)
Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY.
J. Biol. Chem., 270 (49): 29123-8. [PMID:7493937]
3. Sjödin P, Holmberg SK, Akerberg H, Berglund MM, Mohell N, Larhammar D. (2006)
Re-evaluation of receptor-ligand interactions of the human neuropeptide Y receptor Y1: a site-directed mutagenesis study.
Biochem. J., 393 (Pt 1): 161-9. [PMID:16097949]