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Ligand id: 1588
Name: nicotinic acid
View more information in the IUPHAR Pharmacology Education Project: niacin
Molecular properties generated using the CDK
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Soga T, Kamohara M, Takasaki J, Matsumoto S, Saito T, Ohishi T, Hiyama H, Matsuo A, Matsushime H, Furuichi K. (2003)
Molecular identification of nicotinic acid receptor.
Biochem. Biophys. Res. Commun., 303 (1): 364-9. [PMID:12646212]
2. Tunaru S, Kero J, Schaub A, Wufka C, Blaukat A, Pfeffer K, Offermanns S. (2003)
PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect.
Nat. Med., 9 (3): 352-5. [PMID:12563315]
3. Wise A, Foord SM, Fraser NJ, Barnes AA, Elshourbagy N, Eilert M, Ignar DM, Murdock PR, Steplewski K, Green A et al.. (2003)
Molecular identification of high and low affinity receptors for nicotinic acid.
J. Biol. Chem., 278 (11): 9869-74. [PMID:12522134]