- Advanced search
- Immuno Portal
- Malaria Portal
Compound class: Endogenous peptide in human, mouse or rat
Comment: The amino acid sequence of endomorphin-1 is believed to be common across mammalian species .
An endogenous peptide, the gene encoding the endomorphin precursor has not yet been identified .
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Gong J, Strong JA, Zhang S, Yue X, DeHaven RN, Daubert JD, Cassel JA, Yu G, Mansson E, Yu L. (1998)
Endomorphins fully activate a cloned human mu opioid receptor.
FEBS Lett, 439 (1-2): 152-6. [PMID:9849897]
2. Rónai AZ, Király K, Szebeni A, Szemenyei E, Prohászka Z, Darula Z, Tóth G, Till I, Szalay B, Kató E et al.. (2009)
Immunoreactive endomorphin 2 is generated extracellularly in rat isolated L4,5 dorsal root ganglia by DPP-IV.
Regul Pept, 157 (1-3): 1-2. [PMID:19540879]
3. Zadina JE, Hackler L, Ge LJ, Kastin AJ. (1997)
A potent and selective endogenous agonist for the mu-opiate receptor.
Nature, 386 (6624): 499-502. [PMID:9087409]