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Compound class: Endogenous peptide in human, mouse or rat
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Chen J, Kuei C, Sutton S, Wilson S, Yu J, Kamme F, Mazur C, Lovenberg T, Liu C. (2005)
Identification and pharmacological characterization of prokineticin 2 beta as a selective ligand for prokineticin receptor 1.
Mol Pharmacol, 67 (6): 2070-6. [PMID:15772293]
2. Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY. (2002)
Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor.
J Biol Chem, 277 (22): 19276-80. [PMID:11886876]
3. Masuda Y, Takatsu Y, Terao Y, Kumano S, Ishibashi Y, Suenaga M, Abe M, Fukusumi S, Watanabe T, Shintani Y et al.. (2002)
Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors.
Biochem Biophys Res Commun, 293 (1): 396-402. [PMID:12054613]
4. Soga T, Matsumoto Si, Oda T, Saito T, Hiyama H, Takasaki J, Kamohara M, Ohishi T, Matsushime H, Furuichi K. (2002)
Molecular cloning and characterization of prokineticin receptors.
Biochim Biophys Acta, 1579 (2-3): 173-9. [PMID:12427552]