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These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Dickson L, Aramori I, McCulloch J, Sharkey J, Finlayson K. (2006)
A systematic comparison of intracellular cyclic AMP and calcium signalling highlights complexities in human VPAC/PAC receptor pharmacology.
Neuropharmacology, 51 (6): 1086-98. [PMID:16930633]
2. Gourlet P, De Neef P, Cnudde J, Waelbroeck M, Robberecht P. (1997)
In vitro properties of a high affinity selective antagonist of the VIP1 receptor.
Peptides, 18 (10): 1555-60. [PMID:9437716]
3. Gourlet P, Vandermeers A, Vertongen P, Rathe J, De Neef P, Cnudde J, Waelbroeck M, Robberecht P. (1997)
Development of high affinity selective VIP1 receptor agonists.
Peptides, 18 (10): 1539-45. [PMID:9437714]
4. Juarranz MG, Van Rampelbergh J, Gourlet P, De Neef P, Cnudde J, Robberecht P, Waelbroeck M. (1999)
Different vasoactive intestinal polypeptide receptor domains are involved in the selective recognition of two VPAC(2)-selective ligands.
Mol. Pharmacol., 56 (6): 1280-7. [PMID:10570056]