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Synonyms: sodium ion
Compound class: Inorganic
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Bhattacharjee A, Joiner WJ, Wu M, Yang Y, Sigworth FJ, Kaczmarek LK. (2003)
Slick (Slo2.1), a rapidly-gating sodium-activated potassium channel inhibited by ATP.
J Neurosci, 23 (37): 11681-91. [PMID:14684870]
2. Ho IH, Murrell-Lagnado RD. (1999)
Molecular determinants for sodium-dependent activation of G protein-gated K+ channels.
J Biol Chem, 274 (13): 8639-48. [PMID:10085101]
3. Lopatin AN, Nichols CG. (1994)
Internal Na+ and Mg2+ blockade of DRK1 (Kv2.1) potassium channels expressed in Xenopus oocytes. Inward rectification of a delayed rectifier.
J Gen Physiol, 103 (2): 203-16. [PMID:8189205]
4. Sui JL, Chan KW, Logothetis DE. (1996)
Na+ activation of the muscarinic K+ channel by a G-protein-independent mechanism.
J Gen Physiol, 108 (5): 381-91. [PMID:8923264]
5. Yuan A, Santi CM, Wei A, Wang ZW, Pollak K, Nonet M, Kaczmarek L, Crowder CM, Salkoff L. (2003)
The sodium-activated potassium channel is encoded by a member of the Slo gene family.
Neuron, 37 (5): 765-73. [PMID:12628167]