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Compound class: Synthetic organic
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Lerche C, Scherer CR, Seebohm G, Derst C, Wei AD, Busch AE, Steinmeyer K. (2000)
Molecular cloning and functional expression of KCNQ5, a potassium channel subunit that may contribute to neuronal M-current diversity.
J Biol Chem, 275 (29): 22395-400. [PMID:10787416]
2. Ohya S, Sergeant GP, Greenwood IA, Horowitz B. (2003)
Molecular variants of KCNQ channels expressed in murine portal vein myocytes: a role in delayed rectifier current.
Circ Res, 92 (9): 1016-23. [PMID:12690036]
3. Søgaard R, Ljungstrøm T, Pedersen KA, Olesen SP, Jensen BS. (2001)
KCNQ4 channels expressed in mammalian cells: functional characteristics and pharmacology.
Am J Physiol, Cell Physiol, 280 (4): C859-66. [PMID:11245603]
4. Wang HS, Pan Z, Shi W, Brown BS, Wymore RS, Cohen IS, Dixon JE, McKinnon D. (1998)
KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel.
Science, 282 (5395): 1890-3. [PMID:9836639]