grayanotoxin III

Home
Ligands
grayanotoxin III

Ligand id: 2628

Name: grayanotoxin III

Structure and Physico-chemical Properties

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	6
Hydrogen bond donors	6
Rotatable bonds	0
Topological polar surface area	121.38
Molecular weight	370.24
XLogP	0.34
No. Lipinski's rules broken	1

Molecular properties generated using the CDK

Summary
Biological activity
References
Structure

References
1. Kimura T, Yamaoka K, Kinoshita E, Maejima H, Yuki T, Yakehiro M, Seyama I. (2001) Novel site on sodium channel alpha-subunit responsible for the differential sensitivity of grayanotoxin in skeletal and cardiac muscle. Mol. Pharmacol., 60 (4): 865-72. [PMID:11562450]

References

1. Kimura T, Yamaoka K, Kinoshita E, Maejima H, Yuki T, Yakehiro M, Seyama I. (2001)
Novel site on sodium channel alpha-subunit responsible for the differential sensitivity of grayanotoxin in skeletal and cardiac muscle.
Mol. Pharmacol., 60 (4): 865-72. [PMID:11562450]