[125I]SB-236636

Ligand id: 2710

Name: [125I]SB-236636    

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 85.03
Molecular weight 510.07
XLogP 4.48
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Young PW, Buckle DR, Cantello BC, Chapman H, Clapham JC, Coyle PJ, Haigh D, Hindley RM, Holder JC, Kallender H, Latter AJ, Lawrie KW, Mossakowska D, Murphy GJ, Roxbee Cox L, Smith SA. (1998)
Identification of high-affinity binding sites for the insulin sensitizer rosiglitazone (BRL-49653) in rodent and human adipocytes using a radioiodinated ligand for peroxisomal proliferator-activated receptor gamma.
J. Pharmacol. Exp. Ther., 284 (2): 751-9. [PMID:9454824]