Abbreviated name: DHT
Synonyms: 17β-hydroxy-5α-androstan-3-one | 5α-dihydrotestosterone | androstanolone | stanolone
Compound class:
Metabolite
Comment: Dihydrotestosterone is an androgenic metabolite of testosterone, it is the primary contributing factor in male pattern baldness.
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖![]() View more information in the IUPHAR Pharmacology Education Project: dihydrotestosterone |
|
References |
1. Fang H, Tong W, Branham WS, Moland CL, Dial SL, Hong H, Xie Q, Perkins R, Owens W, Sheehan DM. (2003)
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. Chem Res Toxicol, 16 (10): 1338-58. [PMID:14565775] |
2. Tilley WD, Marcelli M, Wilson JD, McPhaul MJ. (1989)
Characterization and expression of a cDNA encoding the human androgen receptor. Proc Natl Acad Sci USA, 86 (1): 327-31. [PMID:2911578] |