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Compound class: Synthetic organic
Comment: The INN-assigned compound aceclidine is a racemic mixture of two enantiomers: S(+)-aceclidine and R(-)-aceclidine. Note that ChEMBL represents this compound without the charge in the entry CHEMBL608828.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Ehlert FJ, Griffin MT, Glidden PF. (1996)
The interaction of the enantiomers of aceclidine with subtypes of the muscarinic receptor.
J Pharmacol Exp Ther, 279 (3): 1335-44. [PMID:8968358]
2. Griffin MT, Figueroa KW, Liller S, Ehlert FJ. (2007)
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.
J Pharmacol Exp Ther, 321 (3): 1193-207. [PMID:17392404]