compound 2g [PMID: 2296036]

Ligand id: 2971

Name: compound 2g [PMID: 2296036]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 59.42
Molecular weight 411.22
XLogP 4.73
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Beck G, Kesseler K, Baader E, Bartmann W, Bergmann A, Granzer E, Jendralla H, von Kerekjarto B, Krause R, Paulus E. (1990)
Synthesis and biological activity of new HMG-CoA reductase inhibitors. 1. Lactones of pyridine- and pyrimidine-substituted 3,5-dihydroxy-6-heptenoic (-heptanoic) acids.
J. Med. Chem., 33 (1): 52-60. [PMID:2296036]