- Advanced search
- Immuno Portal
- Malaria Portal
Synonyms: all-trans-geranylgeranyl diphosphate | all-trans-geranylgeranyl-PP | geranylgeranyl pyrophosphate | geranylgeranyl-PP | GGPP
Compound class: Metabolite or derivative
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Hinson DD, Chambliss KL, Toth MJ, Tanaka RD, Gibson KM. (1997)
Post-translational regulation of mevalonate kinase by intermediates of the cholesterol and nonsterol isoprene biosynthetic pathways.
J Lipid Res, 38 (11): 2216-23. [PMID:9392419]
2. Kavanagh KL, Dunford JE, Bunkoczi G, Russell RG, Oppermann U. (2006)
The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding.
J Biol Chem, 281 (31): 22004-12. [PMID:16698791]