[125I]SB258585

Ligand id: 3245

Name: [125I]SB258585    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 70.26
Molecular weight 487.04
XLogP 3.67
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Hirst WD, Stean TO, Rogers DC, Sunter D, Pugh P, Moss SF, Bromidge SM, Riley G, Smith DR, Bartlett S et al.. (2006)
SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models.
Eur. J. Pharmacol., 553 (1-3): 109-19. [PMID:17069795]