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Synonyms: AF-DX 384 | AFDX-384
Compound class: Synthetic organic
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Croy CH, Chan WY, Castetter AM, Watt ML, Quets AT, Felder CC. (2016)
Characterization of PCS1055, a novel muscarinic M4 receptor antagonist.
Eur J Pharmacol, 782: 70-6. [PMID:27085897]
2. Dörje F, Wess J, Lambrecht G, Tacke R, Mutschler E, Brann MR. (1991)
Antagonist binding profiles of five cloned human muscarinic receptor subtypes.
J Pharmacol Exp Ther, 256 (2): 727-33. [PMID:1994002]