Ligand id: 3296

Name: [3H]7-OH-DPAT    

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 23.47
Molecular weight 247.19
XLogP 3.33
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Lévesque D, Diaz J, Pilon C, Martres MP, Giros B, Souil E, Schott D, Morgat JL, Schwartz JC, Sokoloff P. (1992)
Identification, characterization, and localization of the dopamine D3 receptor in rat brain using 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin.
Proc. Natl. Acad. Sci. U.S.A., 89 (17): 8155-9. [PMID:1518841]
2. Ricci A, Veglio F, Amenta F. (1995)
Radioligand binding characterization of putative dopamine D3 receptor in human peripheral blood lymphocytes with [3H]7-OH-DPAT.
J. Neuroimmunol., 58 (2): 139-44. [PMID:7759603]