Synonyms: 3,4-dihydroxy-L-phenylalanine | Inbrija® (levodopa inhalation powder) | L-DOPA | Sinemet®
levodopa is an approved drug (FDA (1993), EMA (2003))
Compound class:
Metabolite
Comment: L-DOPA is the precursor to the neurotransmitters dopamine collectively known as catecholamines. Used in the treatment of Parkisons disease. Note a deuterated derivative D3 L-DOPA with enhanced properties is under development.
![]() View more information in the IUPHAR Pharmacology Education Project: levodopa |
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References |
1. Lopez VM, Decatur CL, Stamer WD, Lynch RM, McKay BS. (2008)
L-DOPA is an endogenous ligand for OA1. PLoS Biol, 6 (9): e236. [PMID:18828673] |