[125I]relaxin-3-B/INSL5 A chimera   Click here for help

GtoPdb Ligand ID: 3789

Synonyms: [125I]H3-B/INSL5 A chimera
 Ligand is labelled  Ligand is radioactive
Compound class: Peptide
Comment: Synthetic chimeric analogue of human relaxin-3 and human INSL5. The B chain of human relaxin-3 is radiolabelled (using 125 at tyrosine 5) and forms a heteromer with the A chain of human INSL5. For details of the amino acid sequences of the subunits, see the ligand entries relaxin-3 (B chain) and INSL5 (A chain).
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References
1. Liu C, Chen J, Kuei C, Sutton S, Nepomuceno D, Bonaventure P, Lovenberg TW. (2005)
Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7.
Mol Pharmacol, 67 (1): 231-40. [PMID:15465925]