[125I]relaxin-3-B/INSL5 A chimera   Click here for help

GtoPdb Ligand ID: 3789

Synonyms: [125I]H3-B/INSL5 A chimera
 Ligand is labelled  Ligand is radioactive
Compound class: Peptide
Comment: Synthetic chimeric analogue of human relaxin-3 and human INSL5. The B chain of human relaxin-3 is radiolabelled (using 125 at tyrosine 5) and forms a heteromer with the A chain of human INSL5. For details of the amino acid sequences of the subunits, see the ligand entries relaxin-3 (B chain) and INSL5 (A chain).
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
RXFP3 Hs Agonist Agonist 9.3 pKd - 1
pKd 9.3 (Kd 5x10-10 M) [1]
RXFP4 Hs Agonist Agonist 8.9 pKd - 1
pKd 8.9 (Kd 1.2x10-9 M) [1]