Ligand id: 4239

Name: L689560

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 5
Topological polar surface area 90.46
Molecular weight 379.05
XLogP 3.25
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Leeson PD, Carling RW, Moore KW, Moseley AM, Smith JD, Stevenson G, Chan T, Baker R, Foster AC, Grimwood S et al.. (1992)
4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor.
J. Med. Chem., 35 (11): 1954-68. [PMID:1534584]