Synonyms: H 168/68 | Losec® | Prilosec®
omeprazole is an approved drug (FDA (1989))
Compound class:
Synthetic organic
Comment: This approved drug omeprazole is a racemic mixture of the R and S stereoisomers. Omeprazole is a potassium-transporting ATPase inhibitor, commonly referred to as a proton pump inhibitor.
![]() View more information in the IUPHAR Pharmacology Education Project: omeprazole |
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References |
1. Adelstein GW, Yen CH, Haack RA, Yu S, Gullikson G, Price DV, Anglin C, Decktor DL, Tsai H, Keith RH. (1988)
Substituted 2-[(2-benzimidazolylsulfinyl)methyl]anilines as potential inhibitors of H+/K+ ATPase. J Med Chem, 31 (6): 1215-20. [PMID:2836591] |
2. Sanfilippo PJ, Urbanski M, Press JB, Hajos ZG, Shriver DA, Scott CK. (1988)
Synthesis of (aryloxy)alkylamines. 1. Novel antisecretory agents with H+K+-ATPase inhibitory activity. J Med Chem, 31 (9): 1778-85. [PMID:2842503] |