Ligand id: 4489

Name: [11C]GlySar    

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 83.63
Molecular weight 146.07
XLogP -4.04
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Mitsuoka K, Miyoshi S, Kato Y, Murakami Y, Utsumi R, Kubo Y, Noda A, Nakamura Y, Nishimura S, Tsuji A. (2008)
Cancer detection using a PET tracer, 11C-glycylsarcosine, targeted to H+/peptide transporter.
J. Nucl. Med., 49 (4): 615-22. [PMID:18344442]
2. Nabulsi NB, Smith DE, Kilbourn MR. (2005)
[11C]Glycylsarcosine: synthesis and in vivo evaluation as a PET tracer of PepT2 transporter function in kidney of PepT2 null and wild-type mice.
Bioorg. Med. Chem., 13 (8): 2993-3001. [PMID:15781409]