Ligand id: 4575

Name: [14C]TEA    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 0
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 0
Molecular weight 130.16
XLogP 1.56
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Otsuka M, Matsumoto T, Morimoto R, Arioka S, Omote H, Moriyama Y. (2005)
A human transporter protein that mediates the final excretion step for toxic organic cations.
Proc. Natl. Acad. Sci. U.S.A., 102 (50): 17923-8. [PMID:16330770]
2. Tanihara Y, Masuda S, Sato T, Katsura T, Ogawa O, Inui K. (2007)
Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters.
Biochem. Pharmacol., 74 (2): 359-71. [PMID:17509534]
3. Terada T, Masuda S, Asaka J, Tsuda M, Katsura T, Inui K. (2006)
Molecular cloning, functional characterization and tissue distribution of rat H+/organic cation antiporter MATE1.
Pharm. Res., 23 (8): 1696-701. [PMID:16850272]