Ligand id: 4686

Name: L-azetidine-2-carboxylate

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 49.33
Molecular weight 101.05
XLogP -0.54
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Kennedy DJ, Gatfield KM, Winpenny JP, Ganapathy V, Thwaites DT. (2005)
Substrate specificity and functional characterisation of the H+/amino acid transporter rat PAT2 (Slc36a2).
Br. J. Pharmacol., 144 (1): 28-41. [PMID:15644866]
2. Thwaites DT, Anderson CM. (2011)
The SLC36 family of proton-coupled amino acid transporters and their potential role in drug transport.
Br. J. Pharmacol., 164 (7): 1802-16. [PMID:21501141]