rho-TIA   Click here for help

GtoPdb Ligand ID: 507

Abbreviated name: ρ-TIA
Synonyms: ρ-TIA conotoxin | 19-amino acid conopeptide | rho-conotoxin TIA
Comment: From Conus tulipa (Fish-hunting cone snail or Tulip cone)
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1. Chen Z, Rogge G, Hague C, Alewood D, Colless B, Lewis RJ, Minneman KP. (2004)
Subtype-selective noncompetitive or competitive inhibition of human alpha1-adrenergic receptors by rho-TIA.
J. Biol. Chem., 279 (34): 35326-33. [PMID:15194691]
2. Lima V, Mueller A, Kamikihara SY, Raymundi V, Alewood D, Lewis RJ, Chen Z, Minneman KP, Pupo AS. (2005)
Differential antagonism by conotoxin rho-TIA of contractions mediated by distinct alpha1-adrenoceptor subtypes in rat vas deferens, spleen and aorta.
Eur. J. Pharmacol., 508 (1-3): 183-92. [PMID:15680270]
3. Sharpe IA, Thomas L, Loughnan M, Motin L, Palant E, Croker DE, Alewood D, Chen S, Graham RM, Alewood PF et al.. (2003)
Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA.
J. Biol. Chem., 278 (36): 34451-7. [PMID:12824165]