Fas ligand

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Ligands
Fas ligand (Human)

GtoPdb Ligand ID: 5078

Synonyms: apoptosis antigen ligand | CD95L

Compound class: Endogenous peptide in human, mouse or rat

Comment: The TNFSF6 precursor is also cleaved into a soluble form of the ligand.

Species: Human

Summary
Biological activity
References
Structure
Immunopharmacology

References
1. Bidère N, Su HC, Lenardo MJ. (2006) Genetic disorders of programmed cell death in the immune system. Annu Rev Immunol, 24: 321-52. [PMID:16551252]
2. Takahashi T, Tanaka M, Brannan CI, Jenkins NA, Copeland NG, Suda T, Nagata S. (1994) Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell, 76 (6): 969-76. [PMID:7511063]

References

1. Bidère N, Su HC, Lenardo MJ. (2006)
Genetic disorders of programmed cell death in the immune system.
Annu Rev Immunol, 24: 321-52. [PMID:16551252]

2. Takahashi T, Tanaka M, Brannan CI, Jenkins NA, Copeland NG, Suda T, Nagata S. (1994)
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand.
Cell, 76 (6): 969-76. [PMID:7511063]