C5a des-Arg   Click here for help

GtoPdb Ligand ID: 574

Synonyms: C5a des-Arg74
Comment: C5a des-Arg is a natural breakdown product of C5a via the serum enzyme carboxypeptidase B from 74 to 73 amino acids.
Species: Human
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1. Ames RS, Nuthulaganti P, Kumar C. (1996)
In Xenopus oocytes the human C3a and C5a receptors elicit a promiscuous response to the anaphylatoxins.
FEBS Lett, 395 (2-3): 157-9. [PMID:8898085]
2. Cain SA, Monk PN. (2002)
The orphan receptor C5L2 has high affinity binding sites for complement fragments C5a and C5a des-Arg(74).
J Biol Chem, 277 (9): 7165-9. [PMID:11773063]
3. Okinaga S, Slattery D, Humbles A, Zsengeller Z, Morteau O, Kinrade MB, Brodbeck RM, Krause JE, Choe HR, Gerard NP et al.. (2003)
C5L2, a nonsignaling C5A binding protein.
Biochemistry, 42 (31): 9406-15. [PMID:12899627]