C5a des-Arg

Ligand id: 574

Name: C5a des-Arg

Species: Human

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
C5a1 receptor
C5a2 receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
C5a2 receptor Hs Agonist Full agonist 8.6 pEC50 -
pEC50 8.6 (EC50 2.3x10-9 M)
C5a2 receptor Hs Agonist Agonist 7.4 – 7.9 pIC50 - 2,4
pIC50 7.4 – 7.9 (IC50 3.65x10-8 – 1.2x10-8 M) [2,4]
C5a1 receptor Hs Agonist Partial agonist 6.2 – 6.4 pIC50 - 2-3
pIC50 6.2 – 6.4 [2-3]
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Ligand mentioned in the following text fields