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Compound class: Synthetic organic
Comment: Please note that in the article describing its design and discovery galnon is shown as being non-isomeric . This non-isomeric structure is also represented by CID 9961490.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Bartfai T, Lu X, Badie-Mahdavi H, Barr AM, Mazarati A, Hua XY, Yaksh T, Haberhauer G, Ceide SC, Trembleau L et al.. (2004)
Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests.
Proc Natl Acad Sci USA, 101 (28): 10470-5. [PMID:15240875]
2. Lu X, Lundström L, Langel U, Bartfai T. (2005)
Galanin receptor ligands.
Neuropeptides, 39 (3): 143-6. [PMID:15944002]
3. Sollenberg U, Bartfai T, Langel U. (2005)
Galnon--a low-molecular weight ligand of the galanin receptors.
Neuropeptides, 39 (3): 161-3. [PMID:15944006]