aspirin-triggered resolvin D1

Ligand id: 6239

Name: aspirin-triggered resolvin D1

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 14
Topological polar surface area 97.99
Molecular weight 376.22
XLogP 3.23
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Bang S, Yoo S, Yang TJ, Cho H, Hwang SW. (2012)
17(R)-resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception.
Br. J. Pharmacol., 165 (3): 683-92. [PMID:21718307]
2. Krishnamoorthy S, Recchiuti A, Chiang N, Fredman G, Serhan CN. (2012)
Resolvin D1 receptor stereoselectivity and regulation of inflammation and proresolving microRNAs.
Am. J. Pathol., 180 (5): 2018-27. [PMID:22449948]