Ligand id: 6485

Name: AMG-837

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 46.53
Molecular weight 438.14
XLogP 6.75
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

1. Lin DC, Guo Q, Luo J, Zhang J, Nguyen K, Chen M, Tran T, Dransfield PJ, Brown SP, Houze J et al.. (2012)
Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptor.
Mol. Pharmacol., 82 (5): 843-59. [PMID:22859723]