lazabemide

Ligand id: 6640

Name: lazabemide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 68.01
Molecular weight 199.05
XLogP 0.11
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Haefely WE, Kettler R, Keller HH, Da Prada M. (1990)
Ro 19-6327, a reversible and highly selective monoamine, oxidase B inhibitor: a novel tool to explore the MAO-B function in humans.
Adv Neurol, 53: 505-12. [PMID:2122653]
2. Toprakçí M, Yelekçi K. (2005)
Docking studies on monoamine oxidase-B inhibitors: estimation of inhibition constants (K(i)) of a series of experimentally tested compounds.
Bioorg. Med. Chem. Lett., 15 (20): 4438-46. [PMID:16137882]