JNJ-26070109

Ligand id: 6665

Name: JNJ-26070109

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 109.43
Molecular weight 546.02
XLogP 4.84
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Morton MF, Barrett TD, Freedman J, Li L, Rizzolio MC, Prendergast CE, Wu X, Moreno V, Pyati J, Figueroa K et al.. (2011)
JNJ-26070109 [(R)4-bromo-N-[1-(2,4-difluoro-phenyl)-ethyl]-2-(quinoxaline-5-sulfonylamino)-benzamide]: a novel, potent, and selective cholecystokinin 2 receptor antagonist with good oral bioavailability.
J. Pharmacol. Exp. Ther., 338 (1): 328-36. [PMID:21493750]