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Synonyms: isosulfan blue | VM-26 | Vumon®
teniposide is an approved drug (FDA (1992))
Compound class: Synthetic organic
Comment: A podophyllotoxin derivative which achieves cytotoxicity by inhibiting type II topoisomerase activity. Many (85) isomeric alternatives for this compound are listed on PubChem. Click here to link directly to the PubChem listing. The structure shown here matches that shown in the INN document for this compound.
1. Drake FH, Hofmann GA, Bartus HF, Mattern MR, Crooke ST, Mirabelli CK. (1989)
Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II.
Biochemistry, 28 (20): 8154-60. [PMID:2557897]