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Abbreviated name: AMY
Compound class: Endogenous peptide in human, mouse or rat
Species: Mouse, Rat
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Armour SL, Foord S, Kenakin T, Chen WJ. (1999)
Pharmacological characterization of receptor-activity-modifying proteins (RAMPs) and the human calcitonin receptor.
J Pharmacol Toxicol Methods, 42 (4): 217-24. [PMID:11033437]
2. Gingell JJ, Burns ER, Hay DL. (2014)
Activity of pramlintide, rat and human amylin but not Aβ1-42 at human amylin receptors.
Endocrinology, 155 (1): 21-6. [PMID:24169554]
3. Hay DL, Christopoulos G, Christopoulos A, Poyner DR, Sexton PM. (2005)
Pharmacological discrimination of calcitonin receptor: receptor activity-modifying protein complexes.
Mol Pharmacol, 67 (5): 1655-65. [PMID:15692146]
4. Kuwasako K, Cao YN, Nagoshi Y, Tsuruda T, Kitamura K, Eto T. (2004)
Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins.
Mol Pharmacol, 65 (1): 207-13. [PMID:14722252]
5. Zimmermann U, Fluehmann B, Born W, Fischer JA, Muff R. (1997)
Coexistence of novel amylin-binding sites with calcitonin receptors in human breast carcinoma MCF-7 cells.
J Endocrinol, 155 (3): 423-31. [PMID:9487987]