gantenerumab

Ligand id: 6933

Name: gantenerumab

References
1. Bardroff M, Bohrmann B, Brockhaus M, Huber W, Kretzschmar T, Loetscher H, Löhning C, Nordstedt C, Rothe C. (2010)
variable regions peptides for immunizing against amyloid plaque formation; biodrug for dementia, Alzheimer's disease, neuropathy, Down's syndrome, Creutzfeld Jacob disease, Parkinson's disease, amyotropic lateral sclerosis; neuroprotectants; hemostatic agent.
Patent number: US7794719. Assignee: Hoffmann-La Roche Ag, Morphosys Ag. Priority date: 20/02/2002. Publication date: 14/09/2010.
2. Bohrmann B, Baumann K, Benz J, Gerber F, Huber W, Knoflach F, Messer J, Oroszlan K, Rauchenberger R, Richter WF et al.. (2012)
Gantenerumab: a novel human anti-Aβ antibody demonstrates sustained cerebral amyloid-β binding and elicits cell-mediated removal of human amyloid-β.
J. Alzheimers Dis., 28 (1): 49-69. [PMID:21955818]
3. Novakovic D, Feligioni M, Scaccianoce S, Caruso A, Piccinin S, Schepisi C, Errico F, Mercuri NB, Nicoletti F, Nisticò R. (2013)
Profile of gantenerumab and its potential in the treatment of Alzheimer's disease.
Drug Des Devel Ther, 7: 1359-64. [PMID:24255592]