elosulfase alfa   Click here for help

GtoPdb Ligand ID: 7392

Synonyms: BMN 110 | rhGALNS | Vimizim®
Approved drug
elosulfase alfa is an approved drug (EMA & FDA (2014))
Comment: Elosulfase alfa is a recombinant enzyme replacement therapy for galactosamine (N-acetyl)-6-sulfatase (GALNS, P34059) deficiency. The peptide is translated from the human cDNA expressed in CHO cells [1].
1. Dvorak-Ewell M, Wendt D, Hague C, Christianson T, Koppaka V, Crippen D, Kakkis E, Vellard M. (2010)
Enzyme replacement in a human model of mucopolysaccharidosis IVA in vitro and its biodistribution in the cartilage of wild type mice.
PLoS ONE, 5 (8): e12194. [PMID:20808938]